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The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map
The cortical area map is initially patterned by transcription factor (TF) gradients in the neocortical primordium, which define a “protomap” in the embryonic ventricular zone (VZ). However, mechanisms that propagate regional identity from VZ progenitors to cortical plate (CP) neurons are unknown. He...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593833/ https://ncbi.nlm.nih.gov/pubmed/23431145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209076110 |
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