The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map

The cortical area map is initially patterned by transcription factor (TF) gradients in the neocortical primordium, which define a “protomap” in the embryonic ventricular zone (VZ). However, mechanisms that propagate regional identity from VZ progenitors to cortical plate (CP) neurons are unknown. He...

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Detalhes bibliográficos
Main Authors: Elsen, Gina E., Hodge, Rebecca D., Bedogni, Francesco, Daza, Ray A. M., Nelson, Branden R., Shiba, Naoko, Reiner, Steven L., Hevner, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593833/
https://ncbi.nlm.nih.gov/pubmed/23431145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209076110
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