The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase.

We have previously shown that cells mutant for TOP3, a gene encoding a prokaryotic-like type I topoisomerase in Saccharomyces cerevisiae, display a pleiotropic phenotype including slow growth and genome instability. We identified a mutation, sgs1 (slow growth suppressor), that suppresses both the gr...

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Bibliografski detalji
Glavni autori: Gangloff, S, McDonald, J P, Bendixen, C, Arthur, L, Rothstein, R
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC359378/
https://ncbi.nlm.nih.gov/pubmed/7969174
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