Efficiency of insertion versus replacement vector targeting varies at different chromosomal loci.
We have analyzed the targeting frequencies and recombination products generated with isogenic vectors at the fah and fgr loci in embryonic stem cells. A single vector which could be linearized at different sites to generate either a replacement or an insertion vector was constructed for each locus....
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| Опубликовано в:: | Mol Cell Biol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
1994
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359377/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7969173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.12.8385-8390.1994 |
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