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Assessment of 3D models for allergen research
Allergenic proteins must cross-link specific IgE molecules, bound to the surface of mast cells and basophils, to stimulate an immune response. A structural understanding of the allergen-IgE interface is needed to predict cross-reactivities between allergens and to design hypoallergenic proteins. How...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593753/ https://ncbi.nlm.nih.gov/pubmed/23239464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24239 |
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