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Early and Selective Impairments in Axonal Transport Kinetics of Synaptic Cargoes Induced by Soluble Amyloid β-Protein Oligomers

The downstream targets of amyloid β (Aβ)-oligomers remain elusive. One hypothesis is that Aβ-oligomers interrupt axonal transport. Although previous studies have demonstrated Aβ-induced transport blockade, early effects of low-n soluble Aβ-oligomers on axonal transport remain unclear. Furthermore, t...

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Detalhes bibliográficos
Main Authors: Tang, Yong, Scott, David A., Das, Utpal, Edland, Steven D., Radomski, Kryslaine, Koo, Edward H., Roy, Subhojit
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593673/
https://ncbi.nlm.nih.gov/pubmed/22309053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2012.01340.x
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