MicroRNA-18a modulates STAT3 activity through negative regulation of PIAS3 during gastric adenocarcinogenesis

BACKGROUND: MicroRNA (miRNA, miR)-18a is a member of the miR-17–92 cluster, an important locus that is markedly overexpressed in several cancers and associated with cancer development and progression. However, the mechanism of action of the miR-17–92 cluster and its individual miRNAs are largely unk...

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Detalhes bibliográficos
Main Authors: Wu, W, Takanashi, M, Borjigin, N, Ohno, S-i, Fujita, K, Hoshino, S, Osaka, Y, Tsuchida, A, Kuroda, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593546/
https://ncbi.nlm.nih.gov/pubmed/23322197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.587
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