In vitro inhibition of breast cancer spheroid-induced lymphendothelial defects resembling intravasation into the lymphatic vasculature by acetohexamide, isoxsuprine, nifedipin and proadifen

BACKGROUND: As metastasis is the prime cause of death from malignancies, there is vibrant interest to discover options for the management of the different mechanistic steps of tumour spreading. Some approved pharmaceuticals exhibit activities against diseases they have not been developed for. In ord...

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Hlavní autoři: Kretschy, N, Teichmann, M, Kopf, S, Atanasov, A G, Saiko, P, Vonach, C, Viola, K, Giessrigl, B, Huttary, N, Raab, I, Krieger, S, Jäger, W, Szekeres, T, Nijman, S M, Mikulits, W, Dirsch, V M, Dolznig, H, Grusch, M, Krupitza, G
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
Translational Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593542/
https://ncbi.nlm.nih.gov/pubmed/23299527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.580
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