NF-κB mediates the 12(S)-HETE-induced endothelial to mesenchymal transition of lymphendothelial cells during the intravasation of breast carcinoma cells

BACKGROUND: The intravasation of breast cancer into the lymphendothelium is an early step of metastasis. Little is known about the mechanisms of bulky cancer invasion into lymph ducts. METHODS: To particularly address this issue, we developed a 3-dimensional co-culture model involving MCF-7 breast c...

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Detalhes bibliográficos
Main Authors: Vonach, C, Viola, K, Giessrigl, B, Huttary, N, Raab, I, Kalt, R, Krieger, S, Vo, T P N, Madlener, S, Bauer, S, Marian, B, Hämmerle, M, Kretschy, N, Teichmann, M, Hantusch, B, Stary, S, Unger, C, Seelinger, M, Eger, A, Mader, R, Jäger, W, Schmidt, W, Grusch, M, Dolznig, H, Mikulits, W, Krupitza, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142797/
https://ncbi.nlm.nih.gov/pubmed/21629247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.194
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