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Amino acid residues in the CDC25 guanine nucleotide exchange factor critical for interaction with Ras.

Previously we found that negatively charged residues at positions 62, 63, and 69 of H-Ras are involved in binding to the CDC25 guanine nucleotide exchange factor (GEF). Using site-directed mutagenesis, we have changed conserved, positively charged residues of CDC25GEF to glutamic acid. We find the n...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Park, W, Mosteller, R D, Broek, D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1994
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC359350/
https://ncbi.nlm.nih.gov/pubmed/7969149
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