Amino acid residues in the CDC25 guanine nucleotide exchange factor critical for interaction with Ras.
Previously we found that negatively charged residues at positions 62, 63, and 69 of H-Ras are involved in binding to the CDC25 guanine nucleotide exchange factor (GEF). Using site-directed mutagenesis, we have changed conserved, positively charged residues of CDC25GEF to glutamic acid. We find the n...
में बचाया:
| में प्रकाशित: | Mol Cell Biol |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Taylor & Francis
1994
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359350/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7969149/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.12.8117-8122.1994 |
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