CD45 tyrosine phosphatase activity and membrane anchoring are required for T-cell antigen receptor signaling.

T cells that lack the CD45 transmembrane tyrosine phosphatase have a variety of T-cell receptor (TCR) signaling defects that are corrected by reexpression of wild-type CD45 or its intracytoplasmic domains. In this study, a chimeric molecule containing the myristylation sequence of Src and the intrac...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Niklinska, B B, Hou, D, June, C, Weissman, A M, Ashwell, J D
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC359346/
https://ncbi.nlm.nih.gov/pubmed/7526153
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