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CD45 tyrosine phosphatase activity and membrane anchoring are required for T-cell antigen receptor signaling.
T cells that lack the CD45 transmembrane tyrosine phosphatase have a variety of T-cell receptor (TCR) signaling defects that are corrected by reexpression of wild-type CD45 or its intracytoplasmic domains. In this study, a chimeric molecule containing the myristylation sequence of Src and the intrac...
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| Publicado en: | Mol Cell Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
1994
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359346/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7526153/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.12.8078 |
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