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PI3K p110δ regulates T cell cytokine production during primary and secondary immune responses in mice and humans

We have previously described critical and non-redundant roles for the PI3K p110δ during the activation and differentiation of naïve T cells and p110δ inhibitors are currently being developed for clinical use. However, to effectively treat established inflammatory or autoimmune diseases it is importa...

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Bibliografiske detaljer
Main Authors: Soond, Dalya R., Bjørgo, Elisa, Moltu, Kristine, Dale, Verity Q, Patton, Daniel T, Torgersen, Knut Martin, Galleway, Fiona, Twomey, Breda, Clark, Jonathan, Gaston, JS Hill, Taskén, Kjetil, Bunyard, Peter, Okkenhaug, Klaus
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593196/
https://ncbi.nlm.nih.gov/pubmed/20081091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-232330
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