PI3K p110δ regulates T cell cytokine production during primary and secondary immune responses in mice and humans

We have previously described critical and non-redundant roles for the PI3K p110δ during the activation and differentiation of naïve T cells and p110δ inhibitors are currently being developed for clinical use. However, to effectively treat established inflammatory or autoimmune diseases it is importa...

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Autores principales: Soond, Dalya R., Bjørgo, Elisa, Moltu, Kristine, Dale, Verity Q, Patton, Daniel T, Torgersen, Knut Martin, Galleway, Fiona, Twomey, Breda, Clark, Jonathan, Gaston, JS Hill, Taskén, Kjetil, Bunyard, Peter, Okkenhaug, Klaus
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593196/
https://ncbi.nlm.nih.gov/pubmed/20081091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-232330
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