Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target

We investigated the effects of targeting the mitotic regulators aurora kinase A and B in pediatric acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). Aurora protein expression levels in pediatric ALL and AML patient samples were determined by western blot and reverse phase protein...

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Autori principali: Hartsink-Segers, S A, Zwaan, C M, Exalto, C, Luijendijk, M W J, Calvert, V S, Petricoin, E F, Evans, W E, Reinhardt, D, de Haas, V, Hedtjärn, M, Hansen, B R, Koch, T, Caron, H N, Pieters, R, Den Boer, M L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593181/
https://ncbi.nlm.nih.gov/pubmed/22940834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.256
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