Low MAD2 expression levels associate with reduced progression-free survival in patients with high-grade serous epithelial ovarian cancer

Epithelial ovarian cancer (EOC) has an innate susceptibility to become chemoresistant. Up to 30% of patients do not respond to conventional chemotherapy [paclitaxel (Taxol®) in combination with carboplatin] and, of those who have an initial response, many patients relapse. Therefore, an understandin...

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Autori principali: Furlong, Fiona, Fitzpatrick, Patricia, O'Toole, Sharon, Phelan, Sine, McGrogan, Barbara, Maguire, Aoife, O'Grady, Anthony, Gallagher, Michael, Prencipe, Maria, McGoldrick, Aloysius, McGettigan, Paul, Brennan, Donal, Sheils, Orla, Martin, Cara, W Kay, Elaine, O'Leary, John, McCann, Amanda
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd. 2012
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Original Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593171/
https://ncbi.nlm.nih.gov/pubmed/22069160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.3035
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