Derivation and Functional Analysis of Patient-Specific Induced Pluripotent Stem Cells as an In Vitro Model of Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) is an inherited disorder of phagocytes in which NADPH oxidase is defective in generating reactive oxygen species. In this study, we reprogrammed three normal unrelated patient's fibroblasts (p47(phox) and gp91(phox)) to pluripotency by lentiviral transduction...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Jiang, Yan, Cowley, Sally A, Siler, Ulrich, Melguizo, Dario, Tilgner, Katarzyna, Browne, Cathy, Dewilton, Angus, Przyborski, Stefan, Saretzki, Gabriele, James, William S, Seger, Reinhard A, Reichenbach, Janine, Lako, Majlinda, Armstrong, Lyle
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Wiley Subscription Services, Inc., A Wiley Company 2012
विषय:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593166/
https://ncbi.nlm.nih.gov/pubmed/22311747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1053
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