Direct Assessment of Articular Cartilage and Underlying Subchondral Bone Reveals a Progressive Gene Expression Change in Human Osteoarthritic Knees

OBJECTIVE: To evaluate the interaction of articular cartilage (AC) and subchondral bone (SB) through analysis of osteoarthritis (OA)-related genes of site-matched tissue. DESIGN: We developed a novel method for isolating site-matched overlying AC and underlying SB from three and four regions of inte...

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Hlavní autoři: Chou, Ching-Heng, Lee, Chian-Her, Lu, Liang-Suei, Song, I-Wen, Chuang, Hui-Ping, Kuo, San-Yuan, Wu, Jer-Yuarn, Chen, Yuan-Tsong, Kraus, Virginia Byers, Wu, Chia-Chun, Lee, Ming Ta Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593157/
https://ncbi.nlm.nih.gov/pubmed/23220557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2012.11.016
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