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Retinitis pigmentosa: rapid neurodegeneration is governed by slow cell death mechanisms

For most neurodegenerative diseases the precise duration of an individual cell's death is unknown, which is an obstacle when counteractive measures are being considered. To address this, we used the rd1 mouse model for retinal neurodegeneration, characterized by phosphodiesterase-6 (PDE6) dysfu...

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Detalhes bibliográficos
Main Authors: Sahaboglu, A, Paquet-Durand, O, Dietter, J, Dengler, K, Bernhard-Kurz, S, Ekström, P AR, Hitzmann, B, Ueffing, M, Paquet-Durand, F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593146/
https://ncbi.nlm.nih.gov/pubmed/23392176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.12
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