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The impact of microcarrier culture optimization on the glycosylation profile of a monoclonal antibody

Microcarriers are widely used for the large-scale culture of attachment-dependent cells with increased cell densities and, ultimately, higher product yield. In these processes, the specific culture conditions can affect the quality of the product, which is closely related to its glycosylation patter...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Costa, Ana Rita, Withers, Joanne, Rodrigues, Maria Elisa, McLoughlin, Niaobh, Henriques, Mariana, Oliveira, Rosário, Rudd, Pauline M, Azeredo, Joana
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer International Publishing AG 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592997/
https://ncbi.nlm.nih.gov/pubmed/23487430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-2-25
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