Gli1 Deletion Prevents Helicobacter-Induced Gastric Metaplasia and Expansion of Myeloid Cell Subsets

Chronic inflammation in the stomach induces metaplasia, the pre-cancerous lesion that precedes inflammation-driven neoplastic transformation. While Hedgehog signaling contributes to the initiation of some cancers, its role in gastric transformation remains poorly defined. We found that Helicobacter-...

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Detalhes bibliográficos
Main Authors: El-Zaatari, Mohamad, Kao, John Y., Tessier, Art, Bai, Longchuan, Hayes, Michael M., Fontaine, Clinton, Eaton, Kathryn A., Merchant, Juanita L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592845/
https://ncbi.nlm.nih.gov/pubmed/23520544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058935
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