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Oleuropein Aglycone Protects Transgenic C. elegans Strains Expressing Aβ42 by Reducing Plaque Load and Motor Deficit

The presence of amyloid aggregates of the 42 amino acid peptide of amyloid beta (Aβ42) in the brain is the characteristic feature of Alzheimer’s disease (AD). Amyloid beta (Aβ deposition is also found in muscle fibers of individuals affected by inclusion body myositis (sIBM), a rare muscular degener...

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Bibliographische Detailangaben
Hauptverfasser: Diomede, Luisa, Rigacci, Stefania, Romeo, Margherita, Stefani, Massimo, Salmona, Mario
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592812/
https://ncbi.nlm.nih.gov/pubmed/23520540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058893
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