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Bayesian Inference for Generalized Linear Mixed Model Based on the Multivariate t Distribution in Population Pharmacokinetic Study

This article provides a fully Bayesian approach for modeling of single-dose and complete pharmacokinetic data in a population pharmacokinetic (PK) model. To overcome the impact of outliers and the difficulty of computation, a generalized linear model is chosen with the hypothesis that the errors fol...

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Autors principals: Yan, Fang-Rong, Huang, Yuan, Liu, Jun-Lin, Lu, Tao, Lin, Jin-Guan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592804/
https://ncbi.nlm.nih.gov/pubmed/23520504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058369
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