Identification and characterization by antisense oligonucleotides of exon and intron sequences required for splicing.
Certain thalassemic human beta-globin pre-mRNAs carry mutations that generate aberrant splice sites and/or activate cryptic splice sites, providing a convenient and clinically relevant system to study splice site selection. Antisense 2'-O-methyl oligoribonucleotides were used to block a number of se...
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| I publikationen: | Mol Cell Biol |
|---|---|
| Huvudupphov: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Taylor & Francis
1994
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359280/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7935459/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.11.7445-7454.1994 |
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