Physical isolation of nascent RNA chains transcribed by RNA polymerase II: evidence for cotranscriptional splicing.
In order to examine whether splicing can occur cotranscriptionally in mammalian nuclei, we mapped exon-intron boundaries on nascent RNA chains transcribed by RNA polymerase II. A procedure that allows fractionation of nuclei into a chromatin pellet containing DNA, histones, and ternary transcription...
Shranjeno v:
| izdano v: | Mol Cell Biol |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
1994
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359256/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7523861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.11.7219-7225.1994 |
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