Physical isolation of nascent RNA chains transcribed by RNA polymerase II: evidence for cotranscriptional splicing.

In order to examine whether splicing can occur cotranscriptionally in mammalian nuclei, we mapped exon-intron boundaries on nascent RNA chains transcribed by RNA polymerase II. A procedure that allows fractionation of nuclei into a chromatin pellet containing DNA, histones, and ternary transcription...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Wuarin, J, Schibler, U
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359256/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7523861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.11.7219-7225.1994
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