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Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization

Progression to malignancy requires that cells overcome senescence and switch to an immortal phenotype. Thus, exploring the genetic and epigenetic changes that occur during senescence/immortalization may help elucidate crucial events that lead to cell transformation. In the present study, we have glo...

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Bibliografske podrobnosti
Main Authors: Tommasi, Stella, Zheng, Albert, Weninger, Annette, Bates, Steven E., Li, Xuejun Arthur, Wu, Xiwei, Hollstein, Monica, Besaratinia, Ahmad
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592471/
https://ncbi.nlm.nih.gov/pubmed/23143272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1051
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