siSPOTR: a tool for designing highly specific and potent siRNAs for human and mouse

RNA interference (RNAi) serves as a powerful and widely used gene silencing tool for basic biological research and is being developed as a therapeutic avenue to suppress disease-causing genes. However, the specificity and safety of RNAi strategies remains under scrutiny because small inhibitory RNAs...

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Bibliografiske detaljer
Main Authors: Boudreau, Ryan L., Spengler, Ryan M., Hylock, Ray H., Kusenda, Brandyn J., Davis, Heather A., Eichmann, David A., Davidson, Beverly L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Methods Online
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592398/
https://ncbi.nlm.nih.gov/pubmed/22941647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks797
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