Identification of VAR2CSA Domain-Specific Inhibitory Antibodies of the Plasmodium falciparum Erythrocyte Membrane Protein 1 Using a Novel Flow Cytometry Assay

VAR2CSA, a member of the Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family, is a leading candidate for use in vaccines to protect first-time mothers from placental malaria (PM). VAR2CSA, which is comprised of a series of six Duffy binding-like (DBL) domains, binds chondroitin sulf...

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Autori principali: Obiakor, Harold, Avril, Marion, MacDonald, Nicholas J., Srinivasan, Prakash, Reiter, Karine, Anderson, Charles, Holmes, Kevin L., Fried, Michal, Duffy, Patrick E., Smith, Joseph D., Narum, David L., Miller, Louis H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Clinical Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592344/
https://ncbi.nlm.nih.gov/pubmed/23345587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00638-12
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