Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53.

Acidic transcriptional activation domains function well in both yeast and mammalian cells, and some have been shown to bind the general transcription factors TFIID and TFIIB. We now show that two acidic transactivators, herpes simplex virus VP16 and human p53, directly interact with the multisubunit...

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Autores principales: Xiao, H, Pearson, A, Coulombe, B, Truant, R, Zhang, S, Regier, J L, Triezenberg, S J, Reinberg, D, Flores, O, Ingles, C J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC359231/
https://ncbi.nlm.nih.gov/pubmed/7935417
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