Characterization of the Biosynthetic Genes for 10,11-Dehydrocurvularin, a Heat Shock Response-Modulating Anticancer Fungal Polyketide from Aspergillus terreus

10,11-Dehydrocurvularin is a prevalent fungal phytotoxin with heat shock response and immune-modulatory activities. It features a dihydroxyphenylacetic acid lactone polyketide framework with structural similarities to resorcylic acid lactones like radicicol or zearalenone. A genomic locus was identi...

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Detalhes bibliográficos
Main Authors: Xu, Yuquan, Espinosa-Artiles, Patricia, Schubert, Vivien, Xu, Ya-ming, Zhang, Wei, Lin, Min, Gunatilaka, A. A. Leslie, Süssmuth, Roderich, Molnár, István
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Genetics and Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592213/
https://ncbi.nlm.nih.gov/pubmed/23335766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03334-12
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