T Cell Epitope Mapping of JC Polyoma Virus-Encoded Proteome Reveals Reduced T Cell Responses in HLA-DRB1*04:01(+) Donors

JC polyomavirus (JCV) infection is highly prevalent and usually kept in a persistent state without clinical signs and symptoms. It is only during immunocompromise and especially impaired CD4(+) T cell function in the brain, as seen in AIDS patients or natalizumab-treated multiple sclerosis patients,...

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Detalhes bibliográficos
Main Authors: Jelčić, Ilijas, Aly, Lilian, Binder, Thomas M. C., Jelčić, Ivan, Bofill-Mas, Sílvia, Planas, Raquel, Demina, Victoria, Eiermann, Thomas H., Weber, Thomas, Girones, Rosina, Sospedra, Mireia, Martin, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592144/
https://ncbi.nlm.nih.gov/pubmed/23302880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02803-12
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