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Toll-Like Receptor Expression and Induction of Type I and Type III Interferons in Primary Airway Epithelial Cells

Interferons (IFNs) are a critical component of the first line of antiviral defense. The activation of Toll-like receptors (TLRs) expressed by dendritic cells triggers different signaling cascades that result in the production of large amounts of IFNs. However, the functional consequences of TLR acti...

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Autors principals: Ioannidis, Ioannis, Ye, Fang, McNally, Beth, Willette, Meredith, Flaño, Emilio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592129/
https://ncbi.nlm.nih.gov/pubmed/23302870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01956-12
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