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Intranasal Administration of dsRNA Analog Poly(I:C) Induces Interferon-α Receptor-Dependent Accumulation of Antigen Experienced T Cells in the Airways

Polyriboinosinic-polyribocytoidylic acid (pIC), a synthetic dsRNA, acts as an adjuvant that boosts immune responses and protection. Intranasal (IN) administration of pIC has recently been used to adjuvant influenza virus vaccines; however, the effects of IN pIC administration on pulmonary T cell res...

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Detalhes bibliográficos
Main Authors: McNally, Beth, Willette, Meredith, Ye, Fang, Partida-Sanchez, Santiago, Flaño, Emilio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517467/
https://ncbi.nlm.nih.gov/pubmed/23236482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051351
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