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Viral Inhibition of BAK Promotes Murine Cytomegalovirus Dissemination to Salivary Glands

Apoptosis induction is an important host defense mechanism to control viral infection, which is antagonized by viral proteins. Murine cytomegalovirus m41.1 encodes a viral inhibitor of BAK oligomerization (vIBO) that blocks the mitochondrial apoptosis mediator BAK. However, its importance for viral...

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Bibliografiske detaljer
Main Authors: Handke, Wiebke, Luig, Christina, Popović, Branka, Krmpotić, Astrid, Jonjić, Stipan, Brune, Wolfram
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592122/
https://ncbi.nlm.nih.gov/pubmed/23302869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02657-12
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