Repair of an Attenuated Low-Passage Murine Cytomegalovirus Bacterial Artificial Chromosome Identifies a Novel Spliced Gene Essential for Salivary Gland Tropism

The cloning of herpesviruses as bacterial artificial chromosomes (BACs) has revolutionized the study of herpesvirus biology, allowing rapid and precise manipulation of viral genomes. Several clinical strains of human cytomegalovirus (HCMV) have been cloned as BACs; however, no low-passage strains of...

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Foilsithe in:J Virol
Main Authors: Redwood, Alec James, Masters, Laura Lee, Chan, Baca, Leary, Shay, Forbes, Cathy, Jonjić, Stipan, Juranić Lisnić, Vanda, Lisnić, Berislav, Smith, Lee Martin
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2020
Ábhair:
Pathogenesis and Immunity
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592224/
https://ncbi.nlm.nih.gov/pubmed/32847854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01456-20
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