Repair of an Attenuated Low-Passage Murine Cytomegalovirus Bacterial Artificial Chromosome Identifies a Novel Spliced Gene Essential for Salivary Gland Tropism

The cloning of herpesviruses as bacterial artificial chromosomes (BACs) has revolutionized the study of herpesvirus biology, allowing rapid and precise manipulation of viral genomes. Several clinical strains of human cytomegalovirus (HCMV) have been cloned as BACs; however, no low-passage strains of...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Redwood, Alec James, Masters, Laura Lee, Chan, Baca, Leary, Shay, Forbes, Cathy, Jonjić, Stipan, Juranić Lisnić, Vanda, Lisnić, Berislav, Smith, Lee Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592224/
https://ncbi.nlm.nih.gov/pubmed/32847854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01456-20
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