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Influenza A Virus NS1 Induces G(0)/G(1) Cell Cycle Arrest by Inhibiting the Expression and Activity of RhoA Protein

Influenza A virus is an important pathogenic virus known to induce host cell cycle arrest in G(0)/G(1) phase and create beneficial conditions for viral replication. However, how the virus achieves arrest remains unclear. We investigated the mechanisms underlying this process and found that the nonst...

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Detalhes bibliográficos
Main Authors: Jiang, Wei, Wang, Qingtao, Chen, Shuai, Gao, Shijuan, Song, Liping, Liu, Pengyu, Huang, Wenlin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592114/
https://ncbi.nlm.nih.gov/pubmed/23283961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03176-12
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