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Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation.

Ligand stimulation of the platelet-derived growth factor (PDGF) beta-receptor leads to activation of its intrinsic tyrosine kinase and autophosphorylation of the intracellular part of the receptor. The autophosphorylated tyrosine residues mediate interactions with downstream signal transduction mole...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Arvidsson, A K, Rupp, E, Nånberg, E, Downward, J, Rönnstrand, L, Wennström, S, Schlessinger, J, Heldin, C H, Claesson-Welsh, L
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1994
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC359202/
https://ncbi.nlm.nih.gov/pubmed/7935391
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