Reduced Vancomycin Susceptibility in an In Vitro Catheter-Related Biofilm Model Correlates with Poor Therapeutic Outcomes in Experimental Endocarditis Due to Methicillin-Resistant Staphylococcus aureus

Staphylococcus aureus is the most common cause of endovascular infections, including catheter sepsis and infective endocarditis (IE). Vancomycin (VAN) is the primary choice for treatment of methicillin-resistant S. aureus (MRSA) infections. However, high rates of VAN treatment failure in MRSA infect...

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Autors principals: Abdelhady, Wessam, Bayer, Arnold S., Seidl, Kati, Nast, Cynthia C., Kiedrowski, Megan R., Horswill, Alexander R., Yeaman, Michael R., Xiong, Yan Q.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591927/
https://ncbi.nlm.nih.gov/pubmed/23295925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02073-12
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