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Relationship of agr Expression and Function with Virulence and Vancomycin Treatment Outcomes in Experimental Endocarditis Due to Methicillin-Resistant Staphylococcus aureus

The accessory gene regulator (agr) locus has been shown to be important for virulence in several animal models of Staphylococcus aureus infection. However, the role of agr in human infections, and specifically in antibiotic treatment, is controversial. Interestingly, agr dysfunction has been associa...

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Autori principali: Seidl, Kati, Chen, Liang, Bayer, Arnold S., Hady, Wessam Abdel, Kreiswirth, Barry N., Xiong, Yan Q.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232782/
https://ncbi.nlm.nih.gov/pubmed/21968365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05251-11
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