NF-IL6 and AP-1 cooperatively modulate the activation of the TSG-6 gene by tumor necrosis factor alpha and interleukin-1.

Tumor necrosis factor alpha (TNF-alpha) and interleukin-1 (IL-1) activate transcription of the TSG-6 gene in normal human fibroblasts through a promoter region (-165 to -58) that encompasses an AP-1 and a NF-IL6 site. We show by deletion analysis and substitution mutagenesis that both sites are nece...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Klampfer, L, Lee, T H, Hsu, W, Vilcek, J, Chen-Kiang, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359186/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7935377/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.10.6561-6569.1994
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