Kir2.4 Surface Expression and Basal Current Are Affected by Heterotrimeric G-Proteins

Kir2.4, a strongly rectifying potassium channel that is localized to neurons and is especially abundant in retina, was fished with yeast two-hybrid screen using a constitutively active Gα(o1). Here, we wished to determine whether and how Gα(o) affects this channel. Using transfected HEK 293 cells an...

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Bibliographic Details
Main Authors: Sulaiman, Pyroja, Xu, Ying, Fina, Marie E., Tummala, Shanti R., Ramakrishnan, Hariharasubramanian, Dhingra, Anuradha, Vardi, Noga
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Molecular Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591649/
https://ncbi.nlm.nih.gov/pubmed/23339194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.412791
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