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Forskolin-inducible cAMP Pathway Negatively Regulates T-cell Proliferation by Uncoupling the Interleukin-2 Receptor Complex

Cytokine-mediated regulation of T-cell activity involves a complex interplay between key signal transduction pathways. Determining how these signaling pathways cross-talk is essential to understanding T-cell function and dysfunction. In this work, we provide evidence that cross-talk exists between a...

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Hlavní autoři: Rodriguez, Georgialina, Ross, Jeremy A., Nagy, Zsuzsanna S., Kirken, Robert A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591623/
https://ncbi.nlm.nih.gov/pubmed/23341462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.408765
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