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Sarcolipin Protein Interaction with Sarco(endo)plasmic Reticulum Ca(2+)ATPase (SERCA) Is Distinct from Phospholamban Protein, and Only Sarcolipin Can Promote Uncoupling of the SERCA Pump

Sarco(endo)plasmic reticulum Ca(2+)ATPase (SERCA) pump activity is modulated by phospholamban (PLB) and sarcolipin (SLN) in cardiac and skeletal muscle. Recent data suggest that SLN could play a role in muscle thermogenesis by promoting uncoupling of the SERCA pump (Lee, A.G. (2002) Curr. Opin. Stru...

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Autors principals: Sahoo, Sanjaya K., Shaikh, Sana A., Sopariwala, Danesh H., Bal, Naresh C., Periasamy, Muthu
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591597/
https://ncbi.nlm.nih.gov/pubmed/23341466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.436915
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