Nonsense but not missense mutations can decrease the abundance of nuclear mRNA for the mouse major urinary protein, while both types of mutations can facilitate exon skipping.
In an effort to understand the mechanisms by which nonsense codons affect RNA metabolism in mammalian cells, nonsense mutations were generated within the gene for the secretory major urinary protein (MUP) of mice. The translation of MUP mRNA normally begins within exon 1 and terminates within exon 6...
محفوظ في:
| الحاوية / القاعدة: | Mol Cell Biol |
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| المؤلفون الرئيسيون: | , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Taylor & Francis
1994
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359159/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8065364/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.9.6326-6336.1994 |
| الوسوم: |
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