Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance.

The translation of human triosephosphate isomerase (TPI) mRNA normally terminates at codon 249 within exon 7, the final exon. Frameshift and nonsense mutations of the type that cause translation to terminate prematurely at or upstream of codon 189 within exon 6 reduce the level of nuclear TPI mRNA t...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Mol Cell Biol
Päätekijät:	Cheng, J, Belgrader, P, Zhou, X, Maquat, L E
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Taylor & Francis 1994
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359158/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8065363/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.9.6317-6325.1994
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!