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Binding of matrix attachment regions to lamin polymers involves single-stranded regions and the minor groove.

Chromatin in eukaryotic nuclei is thought to be partitioned into functional loop domains that are generated by the binding of defined DNA sequences, named MARs (matrix attachment regions), to the nuclear matrix. We have previously identified B-type lamins as MAR-binding matrix components (M. E. E. L...

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Hlavní autoři: Ludérus, M E, den Blaauwen, J L, de Smit, O J, Compton, D A, van Driel, R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC359156/
https://ncbi.nlm.nih.gov/pubmed/8065361
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