Binding to the Minor Groove of the Double-Strand, Tau Protein Prevents DNA from Damage by Peroxidation

Tau, an important microtubule associated protein, has been found to bind to DNA, and to be localized in the nuclei of both neurons and some non-neuronal cells. Here, using electrophoretic mobility shifting assay (EMSA) in the presence of DNA with different chain-lengths, we observed that tau protein...

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Detalhes bibliográficos
Main Authors: Wei, Yan, Qu, Mei-Hua, Wang, Xing-Sheng, Chen, Lan, Wang, Dong-Liang, Liu, Ying, Hua, Qian, He, Rong-Qiao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2432501/
https://ncbi.nlm.nih.gov/pubmed/18596978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002600
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