Position independence and proper developmental control of gamma-globin gene expression require both a 5' locus control region and a downstream sequence element.

Ítems similars

• Sheltering of gamma-globin expression from position effects requires both an upstream locus control region and a regulatory element 3' to the A gamma-globin gene.
  per: Stamatoyannopoulos, J A, et al.
  Publicat: (1997)
• Developmental regulation of human gamma-globin genes in transgenic mice.
  per: Stamatoyannopoulos, G, et al.
  Publicat: (1993)
• Role of gene order in developmental control of human gamma- and beta-globin gene expression.
  per: Peterson, K R, et al.
  Publicat: (1993)
• Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes.
  per: Peterson, K R, et al.
  Publicat: (1993)
• The proximal element of the beta globin locus control region is not functionally required in vivo.
  per: Kulozik, A E, et al.
  Publicat: (1991)