Rapid and Scalable Plant-based Production of a Cholera Toxin B Subunit Variant to Aid in Mass Vaccination against Cholera Outbreaks

INTRODUCTION: Cholera toxin B subunit (CTB) is a component of an internationally licensed oral cholera vaccine. The protein induces neutralizing antibodies against the holotoxin, the virulence factor responsible for severe diarrhea. A field clinical trial has suggested that the addition of CTB to ki...

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Main Authors: Hamorsky, Krystal Teasley, Kouokam, J. Calvin, Bennett, Lauren J., Baldauf, Keegan J., Kajiura, Hiroyuki, Fujiyama, Kazuhito, Matoba, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591335/
https://ncbi.nlm.nih.gov/pubmed/23505583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002046
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