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DNA methylation represses the murine alpha 1(I) collagen promoter by an indirect mechanism.

Several lines of evidence indicate that DNA methylation plays a role in the transcriptional regulation of the murine alpha 1(I) collagen gene. To study the molecular mechanisms involved, a reporter gene construct containing the alpha 1(I) promoter and part of the first exon linked to the luciferase...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Rhodes, K, Rippe, R A, Umezawa, A, Nehls, M, Brenner, D A, Breindl, M
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359121/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8065328/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.9.5950-5960.1994
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